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Enqiang Chen, Sichuan University, China Updates Copyright 2021 Gu, Fu, Ye, Chen, Li, Zhong, Tang, Chen, Jiang, Hou and Li

in the other outcome, the injured tissue continues to deteriorate, and the mechanism of the persisting damage involves gliosis with the loss of support of neurotrophic factors, persistent inflammatory receptor activation, and changes in microglia and astrocytes that continue to release harmful cytokines, which promote neuronal death and axonal injury